Estrous cycle study on green coconut water in experimentally induced hyperprolactine in female Sprague-Dawleys rats

The objective of present study is to determine the effect of green coconut water on estrous cycle in metoclopramide-induce hyperprolactinemia in female Sprague-Dawley rats. Fifty adult cyclic female Sprague-Dawley rats were used for this study. The animals were treated with green coconut water (GCW) before, after and concurrently with metoclopramide to induce hyperprolactinemia. The posttreated groups demonstrated a statistical comparable result in the number of completed cycles and pattern of cycling while the pre-treated and co-administered groups show significant reduction in the number of completed cycle due to delay on the diestrous phase of the cycle. There was earlier reversal of estrous cyclicity in the green coconut water post-treated rats while the pre-treated and co-administered group did not show reversal of estrous cyclicity. Findings of the present study indicate GCW has fertility enhancing properties by regulating estrous cycle pattern.